Marraffa, in Encyclopedia of Toxicology (Third Edition), 2014. Immunologic The choice of a topical glucocorticoid in patients with allergic contact dermatitis due to polyethylene glycol has been discussed [64R]. Nanosized particles of AFe 2 O 4 (A = Mn, Fe, Co, Ni, or Zn) ferromagnetic materials having a spinel structure are synthesized by deposition from nonaqueous solutions. The process consists of the oxidation of ethylene at a high temperature in the presence of a silver oxide catalyst. With the rapid development of China's ethylene industry and the increased production of diethylene glycol, taking full advantage of the diethylene glycol resources to develop downstream products and expanding the use of diethylene glycol is becoming more and more important. Experimental studies in rats exposed to diethylene glycol clearly showed similarities with rats experiencing ethylene glycol toxicity [57,58]. Under normal conditions, diethylene glycol has no detectable odor; however, under high vapor concentrations, a slightly sweet odor may be detected. HiMedia GRM10145-500ML Diethylene Glycol, 500 mL. DEG is produced by the partial hydrolysis of ethylene oxide. J AOAC Int 81(1):44-50. diethylene glycol, etc ; crosslinking; crystals; gels; nanocapsules; polyethylene glycol; polymerization; pyrogallol; ... An unsaturated polyester resin was synthesized and filled with Cloisite 10A nanoparticles. Industrially, DEG is used to manufacture polyurethanes, plasticizers, and polyester resins. In addition to being versatile, Legacy's diethylene glycol fuel cells are convenient and easy to use. PEGs can be synthesized in linear, branched, Y-shaped, or multi-arm geometries. C.A.S.E. The clinical course and the pathological features have, however, been described in several reports of which the sulfanilamide “Massengil disaster” is probably the best known [55]. The common name ethylene glycol literally means “the glycol derived from ethylene.” Ethylene glycol is by far the largest volume of the glycol products in a variety of applications. 242 DP, … It is a water-soluble liquid; boiling point 245 C, and is soluble in many organic solvents. The results suggested that the renal tubular damage is due to a toxic metabolite, diglycolic acid, and that transporter-mediated uptake leads to toxic intracellular accumulation. Then, 0.76 mL ACC–DEG slurry was injected into the magnesium solution to obtain the magnesium-stabilized ACC. The industry generally operates to maximize MEG production. There is too little information about diethylene glycol poisonings in humans to allow for any absolute recommendations regarding the treatment of acute poisonings. Diethylene glycol dimethacrylate. DEG is primarily synthesized via the partial hydrolysis of ethylene oxide, and is co-produced with ethylene glycol and triethylene glycol. A patient in an acute condition appears inebriated but has no alcohol on his or her breath. It is also incompatible with strong bases. DEG is a widely used solvent. However, the results have been conflicting. Simple, at-site detection of diethylene glycol/ethylene glycol contamination of glycerin and glycerin- based raw materials by thin-layer chromatography. DEG contaminated a shipment of glycerin imported to Haiti from China through Europe. Diethylene glycol is an organic, colorless, almost odorless, and poisonous chemical compound. 2358-84-1. By continuing you agree to the use of cookies. have been synthesized by a low temperature chemical precipitation method. Production of diethylene glycol is generally based on the demand for, and production of, monoethylene glycol as it is a by-product of this production process. It may demonstrate electrophysiological findings consistent with a polyradiculopathy (Martinez-Miguel et al., 2006; Zhou et al., 2002). Diethylene glycol is derived as a co-product with ethylene glycol and triethylene glycol. The influence of diethylene glycol … Diethylene glycol (DEG) is the by-product of the hydration of ethylene oxide. Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings. X-ray powder diffraction results showed that face centered cubic CeO 2 nanoparticles with crystalline size in nanometer scale were formed. Scanning electron microscopy measurement showed that by increasing … Use of diethylene glycol in commercial processes in the past century has led to contamination of consumer products, and there have been more than a few epidemics of poisoning since its introduction during the 20th century. The half-life of DEG is dose dependent and doses of 6 ml kg−1 and 12 ml kg−1 in rats yielded a half-life of 8 and 12 h, respectively. The ethylene oxide is then hydrated to yield diethylene glycol with monoethylene glycol and triethylene glycol as co-products. n = 0 ethylene glycol ("antifreeze") ; n = 1 DEG n = 2 triethylene glycol, TEG, or triglycol is also a colorless odourless viscous liquid. Drug dosage regimens Because polyethylene glycol is used in a large volume for bowel preparation, patient adherence may be poor. Urinary tract The mechanism of diethylene glycol toxicity has been studied in human proximal tubule cells in culture [62E]. It is completely miscible with water and many organic liquids. Diethylene glycol, or DEG, is a colorless, liquid organic compound at room temperature produced by the interaction of ethylene glycol and triethylene glycol. The synthesis of individual oligomers 1,n is described. DIETHYLENE GLYCOL: ICSC: 0619: 2,2'-Oxydiethanol 2,2'-Oxybisethanol Ethylene diglycol 2,2'-Dihydroxyethyl ether 3-Oxypentane-1,5-diol: November 2007: CAS #: 111-46-6 EC Number: 203-872-2 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Combustible. Its toxicity has been assessed. Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. Diethylene glycol is used in the manufacture of unsaturated polyester resins, polyurethanes and plasticizers. The process consists of the oxidation of ethylene at a high temperature in the presence of a silver oxide catalyst. DEG is produced by the partial hydrolysis of ethylene oxide. Unfortunately, outbreaks continue to occur in developing countries following the inadvertent substitution of diethylene glycol for PG or glycerin in elixirs usually intended for children, with mortality rates of 40% to 100%.60–64 (Table 32C-2) The oral LD50 ranges from 4.9 g/kg (rabbits) to 28.2 g/kg (mice), but is only 1.1 to 2.2 g/kg in mice when given intravenously. The product is completely soluble in water, acetone, alcohol, and other organic solvents. 4.1 out of 5 stars 82. MEG is the raw material used in the production of polyester fiber, PET resins, alkyds, and unsaturated polyesters. Both serve as solvents for the liquid-phase synthesis and surface-active agents for the formation of faceted microcrystals. Simply place a can in your cook stove, unscrew the cap, and light the wicks. Viscosity measurements and film‐forming properties indicate the formation of linear coordination polymers or larger ring structures. When released to the atmosphere, vapor-phase diethylene glycol is degraded by reaction with photochemically produced hydroxyl radicals with an estimated half-life of 13 h. Diethylene glycol in air in particulate-phase may be removed by wet deposition. Application To examine the switching effect of Asp, 1.36 mL of MgCl2 (5.88 mM) aqueous solution was first added into 0.94 mL DEG. Geometrical Constraints of Poly(diethylene glycol methyl ether methacrylate) Brushes on Spherical Nanoparticles and Cylindrical Nanowires: Implications for Thermoresponsive Brushes on Nanoobjects DEG ingestion is often associated with limb weakness, multiple cranial neuropathies that include hearing loss and optic nerve involvement, areflexia, and CSF cytoalbuminologic dissociation, mimicking GBS (Baldwin & Sran, 2010; Rollins et al., 2002; Zhou, Zabad, & Lewis, 2002). Patient adherence may be poor field is for validation purposes and should be at. 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